Global Prevention Platform

The Two Leading Killers on Earth Are Largely Preventable.

Cardiovascular Disease and Cancer account for nearly 30 million deaths per year worldwide. The ABCDES Longevity Framework gives you an evidence-based, measurable and actionable way to change that—for yourself, your family and your community.

Evidence-Based • Awareness Driven • Action-Oriented • Global

Mission

Reduce 30 Million Preventable Deaths Annually

Structured prevention against the two leading global killers:

  • Cardiovascular Disease (~20M deaths/year)
  • Cancer (~10M deaths/year)

Sources: WHO Global Health Estimates, Global Burden of Disease Study, CDC, IARC.

30 Million Deaths Per Year.

If this were an infectious disease, the world would mobilize.
This is slower. But it is just as lethal—and highly preventable with structured, measurable action.

  • ~20 million cardiovascular deaths per year (WHO)

  • ~10 million cancer deaths per year (WHO)

  • Obesity in children aged 5–19 has increased 10-fold in the last 40 years (WHO, 2017)

  • Overweight and obesity linked to 13–15 cancers (IARC / WHO)

The ABCDES Longevity Framework translates this global crisis into daily decisions you can measure, monitor, modify and maintain.

Global Health Snapshot

Top 2 causes of death worldwide:
• Cardiovascular disease
• Cancers

Most are driven by modifiable risk factors—blood sugar, blood pressure, cholesterol, diet, movement, toxins, sleep, stress and missed screenings.

Our goal: Make prevention as structured and trackable as financial planning—starting with you, then scaling globally.

The ABCDES Longevity Framework

A global, evidence-based framework for structured prevention against cardiovascular disease and cancer. Each letter represents a measurable, modifiable lever that compounds over decades of your life.

A — A1C

Blood sugar & metabolic stability. Prediabetes is reversible. A1C is your long-term blood sugar report card—and a powerful lever for heart and cancer risk.

B — Blood Pressure

Silent, early and damaging. Hypertension now affects young adults. Every household should own a BP monitor and know how to respond to each range.

C — Cholesterol

Beyond “good” and “bad” cholesterol. LDL, ApoB, triglycerides, HDL and Lp(a) in high-risk families—each gives you a clearer picture of vascular risk.

D — Diet

The Longevity Plate: half to three-quarters plants, a quarter high-quality protein, and a quarter healthy whole grains. Modeled on DASH and Mediterranean patterns.

E — Exercise

150 minutes/week moderate intensity, 30 minutes of walking most days, plus strength training twice weekly. Aim for 7,000–10,000 steps per day—consistency beats intensity.

S — Screenings, Smoking, Stress, Sleep, Standards

S is the multiplier: cancer screenings by decade, stopping smoking and vaping, reducing stress, protecting sleep, and setting non-negotiable standards for your health.

ABCDES Clinical Deep Dive (By Letter)

Each letter of ABCDES has its own dedicated module inside the course, covering why it matters, how to measure it, what ranges mean and exactly what to do next.

A — A1C (Metabolic Stability)

Why it matters
• 100+ million Americans have prediabetes (CDC)
• Diabetes increases cardiovascular and cancer risk

• Leading cause of kidney disease and need for hemodialysis
• Prediabetes is reversible

A1C Ranges & Actions
Normal (<5.7%)
• Maintain consistency
• Annual monitoring

Prediabetes (5.7–6.4%)
• Walk 30 minutes daily (150 min/week moderate activity)
• Reduce added sugars
• Eliminate sugar beverages
• Increase fiber
Recheck in 3 months

Diabetes (≥6.5%)
• Structured medical therapy
• Possible GLP-1 therapy
• Nutrition counseling
• Close 3‑month rechecks
• Weight reduction target 5–10%

Consistency is king.

B — Blood Pressure

Why it matters
• Leading #1 risk factor for death - "the silent killer"

• Hypertension now affects young adults
• ~20% of men 20–40 may have elevated BP
• ~13% of women 20–40 may have elevated BP

Ranges & Actions
Normal (<120/80)
• Maintain exercise & sodium awareness

Elevated (120–129)
• Increase walking
• Reduce sodium
• Stress reduction

Stage 1 (130–139)
• Home BP monitor recommended
• Lifestyle intervention
• Medical evaluation

Stage 2 (≥140)
• Medical therapy
• Strict monitoring
• Recheck in 4–6 weeks

Every household should own a BP monitor.

C — Cholesterol

What to measure
• LDL
• ApoB
• Triglycerides
• HDL
• Lipoprotein(a) in high‑risk families

Ranges & Actions
LDL <70 (high‑risk target)
• Maintain

LDL 70–130
• Diet optimization
• Weight reduction
• Exercise

LDL >130
• Medical therapy discussion
• Aggressive risk factor control

Family history of premature heart disease?
Test Lp(a).

D — Diet & E — Exercise

D is for Diet
• ½–¾ of plate plants (fruits & vegetables)
• ¼ plate high‑quality protein
• ¼ plate healthy whole grains
• Remove sugar beverages
• Reduce ultra‑processed foods

Small changes ripple through metabolic pathways.

E is for Exercise
• 150 minutes/week moderate intensity
• 30 minutes daily walking
• Strength training twice weekly
• Steps: aim for 7,000–10,000/day

Consistency beats intensity.

S — Screenings, Stop Smoking, Stress, Sleep, Steps, Standards

Screenings
• Cancer screenings by decade (20s through 80s)
• Cardiovascular imaging (e.g., coronary calcium score)

Stop Smoking & Vaping
• Air pollution is already a top 5 cause of death globally
• Smoking and vaping add preventable toxins—no need to add insult to injury

Stress & Sleep
• 7–8 hours of restorative sleep
• Meditation 5–10 minutes daily
• Limit alcohol

Steps & Standards
• Daily movement targets
• Clear minimum standards you will not negotiate on for your health.

Decade‑by‑Decade Screening Matrix

Your risks and recommended screenings change every decade. The ABCDES course includes a full decade‑by‑decade matrix, mapped to leading guideline bodies, to show what to test and when and depends on family history and risk factors (i.e. obesity).

High‑level view

20s
• Baseline A1c , BP & and cholesterol
• BMI and waist circumference
• Family history mapping

30s
• Repeat lipids
• A1C if risk factors, BP and Cholesterol

40s
• Coronary calcium score (discussion with clinician)
• Advanced lipids where appropriate

A, B & C

50s
• Mandatory coronary calcium score discussion
• Colonoscopy
• Lung screening (if smoking history)

A, B & C


60s–80s
• Structured cancer screening surveillance
• Cardiovascular imaging based on risk and A, B & C.

Snapshot: Screening by Decade

Decade Key Focus
20s Baseline A1c, BP, lipids, BMI, family history
30s Repeat BP, lipids; A1C if overweight or risk factors
40s A, B, C & Discuss coronary calcium; advanced lipids
50s A, B, C & Discuss Coronary calcium, colonoscopy, lung CT (if smoker)
60s–80s A, B, C & Structured cancer + CV imaging surveillance

Full decade matrix and clinical references are included in the ABCDES Longevity Workbook and course.

Beyond Labs: The 8 Dimensions of Wellness

Longevity is more than numbers. Drawing from the Harvard model of wellness, ABCDES integrates the 8 dimensions of wellness into your prevention plan—and emphasizes the central role of relationships.

  • Physical – ABCDES metrics, movement, sleep and screenings
  • Emotional – stress resilience, mood, coping skills
  • Social – quality of friendships, community and support
  • Intellectual – continuous learning and brain health
  • Spiritual – meaning, purpose and aligned values
  • Occupational – work that supports, not erodes, health
  • Environmental – clean air, low toxins, safe spaces
  • Financial – stability that enables long‑term planning

Relationships as a longevity drug
Long-term studies—from Harvard and beyond—show that the quality of your relationships is one of the strongest predictors of health and lifespan. The ABCDES workbook includes prompts for marriage and relationship health, because prevention is a team sport.

Pre‑Marriage & Partnership Health

Marriage is a lifelong partnership. Health transparency matters before you tie the knot.

  • A1C
  • Lipids & Lp(a)
  • Blood pressure
  • BMI & waist circumference
  • Family history of heart disease or cancer
  • Lifestyle habits: sleep, movement, smoking, alcohol

The ABCDES Workbook includes a dedicated Marriage Health Screening Worksheet to make these conversations structured and supportive.

Download the ABCDES Longevity Workbook

Turn knowledge into a measurable plan. The ABCDES Workbook gives you a structured, repeatable way to track your prevention journey over years—not weeks.

  • Open checkbox trackers for each ABCDES letter
  • Quarterly lab tracking sheets (A1C, lipids, BP, weight)
  • Decade‑based screening checklist
  • Marriage & relationship health screening worksheet
  • 50‑year crossroads checklist (health, work, purpose)
  • Daily water and step trackers
  • Stress & meditation logs
Preview of the ABCDES Longevity Workbook pages

3‑Month Feedback Loop
The workbook is designed around a critical 3‑month feedback loop: test, intervene, and re‑test until your ABCs are corrected. This repetition (habits) is where real longevity gains are made.

Live Training

Webinar: After Your ABCDES Screening—What Next?

Screening is step one. The real impact comes from what you do next—and how consistently you do it over the next 3 months, 3 years and 3 decades.

  • How to interpret your ABCDES results with clinical context
  • Designing a 3‑month correction plan you can actually follow
  • When to involve your clinician—and what to ask for
  • How to repeat the ABC cycle until your numbers normalize
  • Why this 3‑month loop is essential for lifelong longevity

This full ABCDES Longevity Framework course, and global rollout strategy work together to scale prevention worldwide.

Know Your Numbers. Extend Your Life.

The problem: Heart disease and cancer kill ~30 million people annually.
The tragedy: Many of these deaths are preventable.
The solution: A structured ABCDES Longevity Framework you can track.

Reserve your seat today.

No spam. Just evidence‑based tools for structured prevention.

Academic Reference Foundation

ABCDES is built on established global data—not opinion. Every recommendation in the full course is anchored to primary literature or major guideline bodies.

  • World Health Organization Global Health Estimates
  • Global Burden of Disease Study
  • CDC Prediabetes Data
  • WHO Childhood Obesity Report
  • IARC (WHO) Obesity & Cancer Association
  • American Heart Association Blood Pressure Guidelines
  • USPSTF Screening Recommendations


ABCDES becomes the prevention umbrella under a broader longevity ecosystem:

  • ABCDES.org → Prevention
  • Heart & Vascular → Intervention
  • Thoracic & Lung → Early Detection
  • Longevity Institute → Master Platform

In this series & Global Themes
• “Know Your Numbers.”
• “30 Million Deaths. Preventable.”
• “Small Steps. Daily.”
• “Marriage Health Screening.”
• “Mandatory at 50.”

© ABCDES Longevity Framework. All rights reserved. This site is educational and does not replace individualized medical advice.

Built as a Global Prevention Platform to reduce cardiovascular disease and cancer through structured, measurable action.